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Xian-Jun Jiang^a,b, Xiang-Mei Li^a,b, Li-Xia Wang^a,b, Shi-Zhen Wen^a,b, Guo-Zhu Wei^a,b, Ku Yang^c and Fei Wang^a,b

^aBioBioPha Co., Ltd., Kunming 650201, China; ^bReference Substance Branch, National Engineering Research Center for Modernization of Traditional Chinese Medicine, Kunming 650201, China; ^cDepartment of Pharmacy, The People’s Hospital of Fengjie County, Chongqing 404600, China

Abstract

Two hitherto unknown highly modified abietane diterpenoids, namely salviapritin A (1) and salviapritin B (2), were isolated from the ethanol extract of Salvia prionitis, together with 17 known compounds. Their chemical structures were established by extensive spectroscopic methods (ESIMS, HRESIMS, 1D and 2D NMR) and by comparison of their NMR data with those of related analogues. Salviapritin A is the first example of a trinorabietane diterpenoid possessing an acenaphthylene skeleton from the Salvia genus. Additionally, a plausible biogenetic pathway for salviapritin B is proposed.

文章链接：https://www.tandfonline.com/doi/abs/10.1080/10286020.2019.1666827